Human class II major histocompatibility complex (MHC) products are essential initiators of cellular immune responses. There are three major isotypes of human class II MHC molecules; HLA-DR, HLA-DP, and HLA-DQ, each of which consists of an alpha and beta chain. HLA-DR alpha is a polymorphic cell surface glycoprotein that is crucial for the cellular interaction in the immune response. Class II molecules have limited tissue distribution and are predominantly expressed on B lymphocytes and macrophage; these class II molecules present peptides derived from extracellular proteins to T cells.
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HLA-Dra (EP96)
Rabbit Monoclonal
Human class II major histocompatibility complex (MHC) products are essential initiators of cellular immune responses. There are three major isotypes of human class II MHC molecules; HLA-DR, HLA-DP, and HLA-DQ, each of which consists of an alpha and beta chain. HLA-DR alpha is a polymorphic cell surface glycoprotein that is crucial for the cellular interaction in the immune response. Class II molecules have limited tissue distribution and are predominantly expressed on B lymphocytes and macrophage; these class II molecules present peptides derived from extracellular proteins to T cells.
Rabbit Monoclonal
Human class II major histocompatibility complex (MHC) products are essential initiators of cellular immune responses. There are three major isotypes of human class II MHC molecules; HLA-DR, HLA-DP, and HLA-DQ, each of which consists of an alpha and beta chain. HLA-DR alpha is a polymorphic cell surface glycoprotein that is crucial for the cellular interaction in the immune response. Class II molecules have limited tissue distribution and are predominantly expressed on B lymphocytes and macrophage; these class II molecules present peptides derived from extracellular proteins to T cells.
