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ZytoLight® Products for FISH Analysis

Reliable Multi-Target Detection using Fluorescence in situ Hybridization!

ZytoLight® products are designed for the identification of genetic aberrations e.g. translocations, deletions, amplifications, and chromosomal aneuploidies by Fluorescence in situ Hybridization (FISH) in formalin-fixed, paraffin-embedded tissue sections, cell samples, blood or bone marrow smears, and metaphase chromosome spreads.

High Sensitivity and Specificity
ZytoLight® FISH probes are direct labeled using the unique ZytoLight® Direct Label System II providing improved signal intensity. All ZytoLight® single copy (SPEC™) probes are processed by the unique ZytoLight® Repeat Subtraction Technique resulting in advanced specificity and less background. No further blocking of repetitive sequences is needed!

ZytoLight® CEN TM probes hybridize to highly repetitive human satellite DNA sequences of chromosomes producing sharp, bright signals specific for each individual chromosome.

ZytoLight® Kits – Convenient Solutions
For making FISH analysis reliable and user-friendly, all ZytoLight® FISH probes can be combined with the ZytoLight® FISH-Tissue Implementation Kit (Z-2028-5/-20) or the ZytoLight® FISH-Cytology Implementation Kit (Z-2099-20), for FISH analyses on cytology specimens. Both Implementation Kits include all necessary pretreatment solutions, wash buffers and DAPI/DuraTect™ -Solution and a detailed protocol to perform successful FISH experiments.

Additionally, for some major targets, complete kits including probes and all necessary reagents are available.

The ZytoLight® system uses direct labeled FISH probes (1), eliminating the need to detect the probes with fluorophore-coupled antibodies. The probes are detected by fluorescence microscopy using appropriate filter sets (2). Due to an exciter filter (3), full-spectrum light, emitted by the microscope lamp (4), is reduced to light of a defined wavelength that specifically excites the fluorophore of the probe. This light is reflected onto the specimen by a dichroic mirror (5). The fluorophore emits light of longer wavelengths that passes the mirror. Finally, a barrier filter (6) reduces the emitted light to a defined wavelength that can be detected.

For RESEARCH USE ONLY

Item No.DescriptionQuantityPrice
ZYT-Z2004200
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0.2 ml ZytoLight CEN 8 Probe Green 20/Tests,Storage Cond:2-8deg,Delivery Cond:4deg, For RUO // 0,2 mL ZytoLight CEN 8 Sonde verte 20 tests, entreposage:2-8deg, livraison:4deg, pour recherche seulementLogin to see pricing
ZYT-Z200450
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0.05 ml ZytoLight CEN 8 Probe Green 5Tests Storage Cond:2-8deg,Delivery Cond:4deg, For RUO // 0,05 mL ZytoLight CEN 8 Sonde verte 5tests, entreposage:2-8deg, livraison:4deg, pour recherche seulementLogin to see pricing
ZYT-Z2112200
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0.2 ml ZytoLight SPEC RUNX1/RUNX1T1 Dual Color Dual Fusion Probe Green/Orange 20Tests Storage:2-8deg Delivery:4deg, RUO // 0,2 mL ZytoLight SPEC RUNX1/RUNX1T1 Sonde de fusion verte/orange 20 tests, entreposage:2-8deg, livraison:4deg, pour rechercheLogin to see pricing
ZYT-Z211250
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0.05 ml ZytoLight SPEC RUNX1/RUNX1T1 Dual Color Dual Fusion Probe Green/Orange 5Tests Storage: 2-8deg Delivery: 4deg, RUO // 0,05 mL ZytoLight SPEC RUNX1/RUNX1T1 Sonde de fusion verte/orange 5tests, entreposage:2-8deg, livraison:4deg, pour rechercheLogin to see pricing
ZYT-Z2113200
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0.2 ml ZytoLight SPEC PML/RARA Dual Color Dual Fusion Probe Orange/Green 20/Tests,Storage Cond:2-8deg,Delivery Cond:4deg, For RUO // 0,2 mL ZytoLight SPEC PML/RARA Sonde de fusion verte/orange 20 tests, entreposage:2-8deg, livraison:4deg, pour rechercheLogin to see pricing
ZYT-Z211350
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0.05 ml ZytoLight SPEC PML/RARA Dual Color Dual Fusion Probe Orange/Green 5Tests Storage: 2-8deg Delivery: 4deg For RUO // 0,05 mL ZytoLight SPEC PML/RARA Sonde de fusion verte/orange 5tests, entreposage:2-8deg, livraison:4deg, pour rechercheLogin to see pricing
ZYT-Z2168200
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0.2 ml ZytoLight SPEC FGFR1 Dual Color Break Apart Probe Green/Orange 5/Tests,Storage Cond:2-8deg,Delivery Cond:4deg, For RUO // 0,2 mL ZytoLight SPEC FGFR1 Sonde de translocation vert/orange 5 tests, entreposage:2-8deg, livraison:4deg, pour rechercheLogin to see pricing
ZYT-Z216850
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0.05 ml ZytoLight SPEC FGFR1 Dual Color Break Apart Probe Green/Orange 5Tests,Storage Cond:2-8deg,Delivery Cond:4deg, For RUO // 0,05 mL ZytoLight SPEC FGFR1 Sonde de translocation vert/orange 5 tests, entreposage:2-8deg, livraison:4deg, pour rechercheLogin to see pricing
ZYT-Z220750
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0.05 ml ZytoLight SPEC CBFB Dual Color Break Apart Probe Green/Orange 5/Tests,Storage Cond:2-8deg,Delivery Cond:4deg, For RUO // 0,05 mL ZytoLight SPEC CBFB Sonde de translocation verte/orange 5 tests, entreposage:2-8deg, livraison:4deg, pour rechercheLogin to see pricing