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You searched for: BoneSTATION
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Milestone BoneSTATION

Advanced system for fixation and decalcification of bone tissues

The BoneSTATION consists of two work platforms complete with glass modules for fixation/ decalcification. The front platform (for the decalcification step) features a heating plate with infrared sensors for automatic temperature control up to 50°C and magnetic stirring.

The rear platform (for the fixation step) has built-in magnetic stirring only. Two user-friendly work platforms, for easy handling of bone specimens, complete the unit.

The BoneSTATION station can be used with ANY type of fixative/decalcifier, even with strong mineral acids (HCl - HNO3), as all contact surfaces are either glass or PTFE polymer.

The magnetic stirrer assures homogeneity of temperature throughout the solution.

The PTFE cover condenses vapors, generating a reflux of the reagent for consistent and safe protocols at constant pH.
A touch-screen terminal allows the user to optimize, standardize and fully document all the processes.

DECALCIFICATION OF BONE MARROW

While mineral acids offer a faster decalcification rate, their protocols are more time/temperature sensitive and processed specimens are not optimal for molecular studies. A recent report demostrates that in this case, recovery of nucleic acids is dramatically reduced.

For this reason, Milestone favors the use of either formic acid or EDTA as "soft" decalcifiers, more suitable for molecular studies. Longer decalcification times are reduced by the optimized agitation and temperature management featured in the BoneSTATION.


OPTIMIZATION, STANDARDIZATION, DOCUMENTATION

The operator is guided by the touch screen control terminal in setting up standardized and optimized decalcification protocols.

The only manual step of transferring the rack from the fixative container to the decalcifier occours when an audible alarm advises of completion of the fixation step. Continuous stirring assures a consistent flow of fresh decalcifier on the bone surface, accelerating the decalcification process by influencing the equilibrium: (Bone) Ca++ <--> Ca++ (Solution)

Combining agitation with increased temperature management accelerates the rates of fixation/ decalcification. On completion of both steps, the bone specimens are processed by conventional or rapid microwave technology. Full documentation can be obtained through the provided USB port.

BoneSTATION typical protocols for bone marrows

FixationDecalcificationTemperatureTotal Time
Formalin 10%MOLdecal°CFixation + Decalcification
4h36h2740h
1h 30’16h 30’3718h
1h4h505h
FixationDecalcificationTemperatureTotal Time
Formalin 10%Formic 10%°CFixation + Decalcification
4h4h278h
1h 30’1h 30’373h
1h1h502h
Item No.DescriptionQuantityPrice
MIL-67481
/contentonly.aspx?file=images/items/MIL-67481_t.* does not exist
45/K HISTOMODULES KIT for decalcification and fixation of up to 4 cassettesLogin to see pricing
MIL-67701
BoneStation: Fixation/Decalcification Processor for Bone Tissues // Instrument pour fixation et décalcification BoneStation de MilestoneLogin to see pricing
MIL-67724
/contentonly.aspx?file=images/items/MIL-67724_t.* does not exist
Dish Glass Containers 2/EALogin to see pricing
MIL-67728
/contentonly.aspx?file=images/items/MIL-67728_t.* does not exist
Kit Labels for White HolderLogin to see pricing
MIL-67757V
/contentonly.aspx?file=images/items/MIL-67757V_t.* does not exist
White Holder for Glass Vessel EALogin to see pricing
MIL-67850
/contentonly.aspx?file=images/items/MIL-67850_t.* does not exist
Bonestation Rack 16 Megacassette // PORTOIR POUR 16 MEGA CASSETTES UNITÉLogin to see pricing
MIL-67854
/contentonly.aspx?file=images/items/MIL-67854_t.* does not exist
BoneSTATION Rack 30 Megacassette // PORTOIR POUR 30 CASSETTES UNITÉLogin to see pricing
MIL-67855
/contentonly.aspx?file=images/items/MIL-67855_t.* does not exist
BoneSTATION Rack 6 SuperMega Cassette // PORTOIR POUR 6 SUPER MEGA CASSETTES UNITÉLogin to see pricing
MIL-67857
/contentonly.aspx?file=images/items/MIL-67857_t.* does not exist
Glass Container (for the histomodule /EALogin to see pricing
MIL-67858
/contentonly.aspx?file=images/items/MIL-67858_t.* does not exist
White Lid for Glass Vessel EALogin to see pricing
MIL-67860
/contentonly.aspx?file=images/items/MIL-67860_t.* does not exist
Internal Divider BoneSTATION/BoneSTATION ONE for decalcification of large specimenLogin to see pricing