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Milestone MoL-DECALCIFIER
EDTA based decalcifying solution (no acid/bases buffers)
For faster decalcification time, the process with EDTA is best carried out at a pH value of 7.2-7.4. Milestone has developed an innovative, pure EDTA solution, based on a stoichiometric mixture of bibasic or tribasic EDTA to reach this pH value without the addition of an acid/base buffer. The combination of increased temperature, stirring and the MoL-DECALCIFIER, during the decalcificacion phase allows fixation, decalcification and processing of bone marrows within 48 hours.
OPTIMIZED MOLECULAR RESULTS A presentation* during the “First Symposium on Pre-analytic of Pathological Specimens - Berlin March 2013” reported the first results on H&E, IHC, FISH and molecular using the Milestone decalcifying solution MoL-DECALCIFIER on bone marrow trephine biopsies.
*Bone marrow work-up, Ioannis Anagnostopoulos Institute for Pathology Charité – Campus Mitte, Berlin Germany.
EDTA based decalcifying solution (no acid/bases buffers)
For faster decalcification time, the process with EDTA is best carried out at a pH value of 7.2-7.4. Milestone has developed an innovative, pure EDTA solution, based on a stoichiometric mixture of bibasic or tribasic EDTA to reach this pH value without the addition of an acid/base buffer. The combination of increased temperature, stirring and the MoL-DECALCIFIER, during the decalcificacion phase allows fixation, decalcification and processing of bone marrows within 48 hours.
OPTIMIZED MOLECULAR RESULTS A presentation* during the “First Symposium on Pre-analytic of Pathological Specimens - Berlin March 2013” reported the first results on H&E, IHC, FISH and molecular using the Milestone decalcifying solution MoL-DECALCIFIER on bone marrow trephine biopsies.
*Bone marrow work-up, Ioannis Anagnostopoulos Institute for Pathology Charité – Campus Mitte, Berlin Germany.
